BDBM50344535 4-(2-(4-(4-ethylpiperazin-1-yl)phenylamino)benzo[d]oxazol-5-yloxy)-N-methylpicolinamide::CHEMBL1778400

SMILES CCN1CCN(CC1)c1ccc(Nc2nc3cc(Oc4ccnc(c4)C(=O)NC)ccc3o2)cc1

InChI Key InChIKey=ZWGXLMYFYRQJBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344535   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50344535(4-(2-(4-(4-ethylpiperazin-1-yl)phenylamino)benzo[d...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed