BDBM50344541 4-(2-(4-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N-methylpicolinamide::CHEMBL1778394

SMILES CCc1ccc(Nc2nc3cc(Oc4ccnc(c4)C(=O)NC)ccc3o2)cc1

InChI Key InChIKey=CWVHILKBNYAQET-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344541   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50344541(4-(2-(4-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N...)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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