BDBM50344848 3-(benzo[d][1,3]dioxol-5-yl)-1-(3,4-difluorobenzyl)-3-hydroxyindolin-2-one::CHEMBL1780040

SMILES OC1(C(=O)N(Cc2ccc(F)c(F)c2)c2ccccc12)c1ccc2OCOc2c1

InChI Key InChIKey=WAPTXLDVFGSBRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344848   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344848(3-(benzo[d][1,3]dioxol-5-yl)-1-(3,4-difluorobenzyl...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed