BDBM50344849 3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(4-(trifluoromethyl)benzyl)indolin-2-one::CHEMBL1780041

SMILES OC1(C(=O)N(Cc2ccc(cc2)C(F)(F)F)c2ccccc12)c1ccc2OCOc2c1

InChI Key InChIKey=XOXGNUVRQAZNPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344849   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344849(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(4-(trifl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed