BDBM50345539 CHEMBL1784336::N-(1-(cyclobutanecarbonyl)-4-((4-(4-fluoro-2-methylphenethyl)piperidin-1-ylsulfonyl)methyl)piperidin-4-yl)-N-hydroxyformamide::US10322143, Compound 15a
SMILES Cc1cc(F)ccc1CCC1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)C1CCC1)N(O)C=O
InChI Key InChIKey=VKMTZVHITCDFFV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50345539
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ADAMTS-4 assessed as substrate cleavage after 16 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Protein concentrations were measured using the Micro BCA Protein Assay Kit (Pierce/Thermo Scientific, IL). Sample buffer was mixed with 5-25 μg ...More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of ADAMTS-5 assessed as substrate cleavage after 16 hrs by fluorescence assayMore data for this Ligand-Target Pair