BDBM50345956 9-(2-Methyl-allylamino)-3-p-tolyl-3H-thieno[2,3-d:4,5-d']dipyrimidin-4-one::CHEMBL1784055

SMILES CC(=C)CNc1ncnc2sc3c(ncn(-c4ccc(C)cc4)c3=O)c12

InChI Key InChIKey=GHYHCRPMRUPLNK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345956   

TargetMetabotropic glutamate receptor 1(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345956(9-(2-Methyl-allylamino)-3-p-tolyl-3H-thieno[2,3-d:...)
Affinity DataKi:  2.90nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345956(9-(2-Methyl-allylamino)-3-p-tolyl-3H-thieno[2,3-d:...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345956(9-(2-Methyl-allylamino)-3-p-tolyl-3H-thieno[2,3-d:...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed