BDBM50345977 5-(4-isopropylphenylsulfonyl)-3-(1-methylpiperidin-4-yl)-1H-indazole::CHEMBL1783582

SMILES CC(C)c1ccc(S(=O)(=O)c2ccc3[nH]nc(C4CCN(C)CC4)c3c2)cc1

InChI Key InChIKey=QWHMNVFMPYFMCB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345977   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345977BDBM50345977(5-(4-isopropylphenylsulfonyl)-3-(1-methylpiperidin...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345977BDBM50345977(5-(4-isopropylphenylsulfonyl)-3-(1-methylpiperidin...)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed