BDBM50346359 20S-[o-(trifluoromethyl)benzylamino]-16alpha-hydroxy-4beta,14alpha-dimethyl-9,19-cyclo-{2'-isopropyl-5',6'-dihydro-4'alphaH-[1',3']thiazino[4',5':3,4]}-5alpha,9beta-pregnan-11-one::CHEMBL1783516

SMILES CC(C)C1=N[C@H]2CC[C@]34C[C@@]33[C@@H](CC[C@H]4[C@]2(C)CS1)[C@]1(C)C[C@@H](O)[C@H]([C@H](C)N(C)Cc2ccccc2C(F)(F)F)[C@@]1(C)CC3=O

InChI Key InChIKey=YTWWSBXEMIYTEK-NGZBDLKASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346359   

TargetAcetylcholinesterase(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50346359(20S-[o-(trifluoromethyl)benzylamino]-16alpha-hydro...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by spectroscopic Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electric eel)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50346359(20S-[o-(trifluoromethyl)benzylamino]-16alpha-hydro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by spectroscopic Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50346359(20S-[o-(trifluoromethyl)benzylamino]-16alpha-hydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine iodide as substrate by spectroscopic Ellmans methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed