BDBM50346553 CHEMBL1797937

SMILES COc1ccc(cc1)C(=O)Oc1ccc(CCn2c(NC(=O)c3ccc(cc3)C(F)(F)F)nc3cc(ccc23)C(O)=O)cc1

InChI Key InChIKey=OWNQZZTXPWICRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50346553   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346553(CHEMBL1797937)
Affinity DataIC50: 106nMAssay Description:Inhibition of lysine methyltransferase G9aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346553(CHEMBL1797937)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition GST-tagged G9a (685 to 1000 residues) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346553(CHEMBL1797937)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346553(CHEMBL1797937)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of G9a (685 to 1000 residues ) (unknown origin) expressed in Escherichia coli BL21 using H3(1 to 20)cys as substrate by spectrometry based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346553(CHEMBL1797937)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed