BDBM50346559 CHEMBL1795624

SMILES FC(F)(F)c1ccc(Cn2sc3ncccc3c2=O)cc1

InChI Key InChIKey=UQVNCGIZTSUQOC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50346559   

TargetHistone acetyltransferase KAT2B(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  2.55E+4nMAssay Description:Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase KAT2B(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase p300(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  5.92E+3nMAssay Description:Inhibition of N-terminal His-tagged human p300 HAT (1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase KAT2A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  8.74E+4nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged GCN5 HAT domain (362 to 837 residues) expressed in baculovirus infected Sf9 cells using histon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of N-terminal GST-tagged human CBP HAT(1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone acetyltransferase KAT2B(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50346559(CHEMBL1795624)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PCAF HAT domain (493 to 657 residues) expressed in Escherichia coli (BL21 D3) using histone H3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed