BDBM50348293 CHEMBL1800118

SMILES COC1(CCCCCC1)c1nnc2c(Oc3cccc(Cl)c3C)cccn12

InChI Key InChIKey=GNIMESYUUSFCOQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348293   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348293(CHEMBL1800118)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human 11beta-HSD-1 expressed in HEK293 cells assessed as [3H]cortisol level by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348293(CHEMBL1800118)
Affinity DataEC50:  150nMAssay Description:Transactivation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348293(CHEMBL1800118)
Affinity DataIC50: 327nMAssay Description:Inhibition of mouse 11beta-HSD-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed