BDBM50348296 CHEMBL1800121

SMILES Cc1c(Cl)cccc1Oc1cccn2c(CC3CC4CCC3C4)nnc12

InChI Key InChIKey=JQYYWVQHGKKNJP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348296   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348296(CHEMBL1800121)
Affinity DataEC50:  150nMAssay Description:Transactivation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348296(CHEMBL1800121)
Affinity DataIC50: 163nMAssay Description:Inhibition of human 11beta-HSD-1 expressed in HEK293 cells assessed as [3H]cortisol level by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348296(CHEMBL1800121)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed