BDBM50349990 CHEMBL1813015

SMILES CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCc3ccccc3C2)c1

InChI Key InChIKey=ZNZCGEXKQOUCKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50349990   

LigandPNGBDBM50349990(CHEMBL1813015)
Affinity DataIC50: 900nMAssay Description:Inhibition of 30% inactivated human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349990(CHEMBL1813015)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349990(CHEMBL1813015)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human Erg expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349990(CHEMBL1813015)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human cardiac sodium channel Nav1.5 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed