BDBM503505 N-(2,3-dihydroxypropyl)-2-({4-[N- (4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl)-N'- hydroxycarbamimidoyl]-1,2,5- oxadiazol-3-yl}oxy)acetamide::US11034661, Example 12

SMILES OCC(O)CNC(=O)COc1nonc1\C(NC1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=QZMVJQOFKAKKKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503505   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM503505(N-(2,3-dihydroxypropyl)-2-({4-[N- (4-fluorobicycl...)
Affinity DataIC50: 700nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent