BDBM503517 N-[(1S)-6-fluoro-2,3-dihydro-1H- inden-1-yl]-N'-hydroxy-4-[2- (sulfamoylamino)ethoxy]-1,2,5- oxadiazole-3-carboximidamide::US11034661, Example 24

SMILES NS(=O)(=O)NCCOc1nonc1\C(N[C@H]1CCc2ccc(F)cc12)=N\O

InChI Key InChIKey=CKQPHNIFWWVZTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503517   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM503517(N-[(1S)-6-fluoro-2,3-dihydro-1H- inden-1-yl]-N'-h...)
Affinity DataIC50: 421nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent