BDBM50352061 CHEMBL1824022

SMILES COc1ccc(nn1)-c1ccc(Cl)c(c1)C(=O)NCC1(O)CCCCCC1

InChI Key InChIKey=AEMWRIGKOGGMDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352061   

TargetP2X purinoceptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352061(CHEMBL1824022)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at P2X7R expressed in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL-1beta releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352061(CHEMBL1824022)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352061(CHEMBL1824022)
Affinity DataIC50:  280nMAssay Description:Antagonist activity at P2X7R expressed in LPS-activated human monocytes assessed as inhibition of ATP-induced IL-1beta release in presence of low ser...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed