BDBM50352733 CHEMBL1823060::US8835436, Example 117

SMILES CCCc1nc(cn1-c1ccccc1)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=NFNYZLRYJMHHBL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352733   

TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352733BDBM50352733(CHEMBL1823060 | US8835436, Example 117)
Affinity DataIC50: 16.8nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 50352733BDBM50352733(CHEMBL1823060 | US8835436, Example 117)
Affinity DataIC50: 103nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 50352733BDBM50352733(CHEMBL1823060 | US8835436, Example 117)
Affinity DataIC50: 103nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 50352733BDBM50352733(CHEMBL1823060 | US8835436, Example 117)
Affinity DataIC50: 133nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandChemical structure of BindingDB Monomer ID 50352733BDBM50352733(CHEMBL1823060 | US8835436, Example 117)
Affinity DataIC50: 133nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed