BDBM50353018 CHEMBL1821980::CHEMBL1852660

SMILES NC1CCc2c(Br)ccc(-c3ccccc3)c2CC1=O

InChI Key InChIKey=XFZZDIHCNHYESF-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50353018   

TargetAminopeptidase N(Pig)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of porcine kidney APN using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAminopeptidase N(Human)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human APNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAminopeptidase N(Pig)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAminopeptidase N(Mouse)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.200nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAminopeptidase N(Human)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of Aeromonas proteolytica aminopeptidase using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytosol aminopeptidase(Bovine)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of bovine kidney cytosolic leucine aminopeptidase using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed