BDBM50353351 CHEMBL1831075
SMILES Cn1c2c3C(Oc4ccc(cc4-n3c(-c3ccccc3)c2c(=O)n(C)c1=O)C(O)=O)c1ccc(Br)o1
InChI Key InChIKey=GNHIGSRGYXEQEP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50353351
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4...More data for this Ligand-Target Pair