BDBM50353649 CHEMBL1829835

SMILES OC(=O)CC(Cc1nc2ccc(I)cc2[nH]1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=QUWVIJIYNFIZHM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353649   

TargetProtein kinase C zeta type(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353649(CHEMBL1829835)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PKCzeta in human U937 cells assessed as inhibition of TNFalpha-induced NF-kB activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353649(CHEMBL1829835)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of human PKCzeta assessed as phosphorylation reaction after 4 mins incubation by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50353649(CHEMBL1829835)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human PKCzeta assessed as [gamma32P]ATP utilization using myelin basic protein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed