BDBM503540 N-[(7S)-4-fluorobicyclo[4.2.0]octa- 1,3,5-trien-7-yl]-N'-hydroxy-4-{[1- (1-hydroxycyclopropane-1- carbonyl)azetidin-3-yl]oxy}-1,2,5- oxadiazole-3-carboximidamide::US11034661, Example 47

SMILES O\N=C(/N[C@H]1Cc2ccc(F)cc12)c1nonc1OC1CN(C1)C(=O)C1(O)CC1

InChI Key InChIKey=FNZKQTWPACAOSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503540   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM503540(N-[(7S)-4-fluorobicyclo[4.2.0]octa- 1,3,5-trien-7...)
Affinity DataIC50: 56.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent