BDBM50354423 CHEMBL1836845

SMILES Clc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)ccc1C(=O)N1CCNC2(CC2)C1

InChI Key InChIKey=PKUNWOUAVLHPIJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354423   

TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354423(CHEMBL1836845)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354423(CHEMBL1836845)
Affinity DataIC50:  13nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354423(CHEMBL1836845)
Affinity DataIC50:  945nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354423(CHEMBL1836845)
Affinity DataIC50:  33nMAssay Description:Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed