BDBM50354441 CHEMBL1836813

SMILES COC1CCN(CC1)C(=O)c1ccc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)cc1Cl

InChI Key InChIKey=BZBBQXMBSCKMNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354441   

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354441(CHEMBL1836813)
Affinity DataIC50:  137nMAssay Description:Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354441(CHEMBL1836813)
Affinity DataIC50:  60nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354441(CHEMBL1836813)
Affinity DataIC50:  10nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed