BDBM50355090 CHEMBL1835313

SMILES CCC(C)O[C@H]1CCN([C@@H]1C(=O)N[C@H]1CC(=O)OC1O)C(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C

InChI Key InChIKey=DKZCVXXTAXUVCL-OWVMPFOQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355090   

TargetCaspase-2(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355090(CHEMBL1835313)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-3(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355090(CHEMBL1835313)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-2(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355090(CHEMBL1835313)
Affinity DataIC50:  413nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-3(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355090(CHEMBL1835313)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed