BDBM50355521 CHEMBL1910545
SMILES Cc1ccc(Cn2cc(CN(C3CC3)C(=O)[C@H]3CNCC[C@]3(O)c3ccc(F)c(F)c3)c3c(F)cccc23)cn1
InChI Key InChIKey=LVQKKHWEPPQIMP-XJFCNFDWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50355521
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant renin in human plasma using QXL520-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-(5-FAM) as Q-FRET substrate after 1 hr by ...More data for this Ligand-Target Pair