BDBM503559 N-((1R,3s)-3-((4-((Z)-N-((S)-4- fluorobicyclo[4.2.0]octa- 1(6),2,4-trien-7-yl)-N'- hydroxycarbamimidoyl)- 1,2,5-oxadiazol-3- yl)oxy)cyclobutyl)-2- hydroxy-2-methylpropanamide::US11034661, Example 66

SMILES CC(C)(O)C(=O)N[C@H]1C[C@H](C1)Oc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=KOOHMEFPVRQNDG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503559   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM503559(N-((1R,3s)-3-((4-((Z)-N-((S)-4- fluorobicyclo[4.2...)
Affinity DataIC50: 167nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent