BDBM503562 US11034670, Ex. 2

SMILES NC(=O)c1ccc(N2CCN(CC2)C(=O)CCc2nc3ccccc3c(=O)[nH]2)c(Cl)c1

InChI Key InChIKey=KJYNUBQNUKNDSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503562   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503562(US11034670, Ex. 2)
Affinity DataIC50: 7nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Mitobridge

US Patent
LigandPNGBDBM503562(US11034670, Ex. 2)
Affinity DataIC50: 69nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent