BDBM50356366 CHEMBL1911416

SMILES Fc1cccc(F)c1Cn1cc(C(=O)Nc2ccc(cc2)N2CCOCC2)c(=O)c2ncccc12

InChI Key InChIKey=MWFHVQNNTSBGCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50356366   

LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 379nMAssay Description:Inhibition of human recombinant PDE4A4 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE4 (unknown origin) by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using [3H]cAMP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50356366(CHEMBL1911416)
Affinity DataIC50: 823nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed