BDBM503571 US11034670, Ex. 11

SMILES O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(CC1)c1ccc(cn1)C#N

InChI Key InChIKey=NVYAWMBGKKEULL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503571   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503571(US11034670, Ex. 11)
Affinity DataIC50: 6nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Mitobridge

US Patent
LigandPNGBDBM503571(US11034670, Ex. 11)
Affinity DataIC50: 338nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent