BDBM50357454 CHEMBL1917878

SMILES O=C(N[C@@H]1c2ccccc2-c2c1cccc2-c1nc2ccncc2[nH]1)c1ccnc2[nH]ccc12

InChI Key InChIKey=UIRMQSUQFQMQHL-XMMPIXPASA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357454   

TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataIC50:  30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock protein HSP 90-beta(Human)
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed