BDBM503578 6-[4-[3-(6-fluoro-4-oxo-3H-quinazolin-2-yl)propanoyl]piperazin-1-yl]pyridine-3-carbonitrile::US11034670, Ex. 18

SMILES Fc1ccc2nc(CCC(=O)N3CCN(CC3)c3ccc(cn3)C#N)[nH]c(=O)c2c1

InChI Key InChIKey=ZXSZFRRHHIPVGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503578   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503578(6-[4-[3-(6-fluoro-4-oxo-3H-quinazolin-2-yl)propano...)
Affinity DataIC50: 7nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Mitobridge

US Patent
LigandPNGBDBM503578(6-[4-[3-(6-fluoro-4-oxo-3H-quinazolin-2-yl)propano...)
Affinity DataIC50: 216nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent