BDBM50358109 CHEMBL1915943

SMILES COc1cccc(CN(C)C(=O)c2ccc(s2)-c2cccc(OC)c2)c1

InChI Key InChIKey=CRYBGCSJAOVZFN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50358109   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50358109(CHEMBL1915943)
Affinity DataIC50:  370nMAssay Description:Inhibition of human placental 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50358109(CHEMBL1915943)
Affinity DataIC50:  371nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50358109(CHEMBL1915943)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human placental 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins by radio flow detector-based HPLC analysis in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50358109(CHEMBL1915943)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human placental 17beta-HSD1 cytosolic fraction using tritiated estrone as substrate assessed as formation of estradiol by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed