BDBM50358328 CHEMBL1922677

SMILES FC(F)(F)c1oc(nc1C(=O)Nc1ccc(nc1)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=ZEWGQRPXLQDDLR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358328   

TargetDiacylglycerol O-acyltransferase 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358328(CHEMBL1922677)
Affinity DataEC50:  840nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358328(CHEMBL1922677)
Affinity DataIC50:  160nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed