BDBM50358854 CHEMBL1923440

SMILES Cc1[nH]c(C(=O)N[C@@H]2CCN(C[C@@H]2F)c2ncc(s2)C(O)=O)c(Cl)c1Cl

InChI Key InChIKey=BGDGHNSKANYMHF-JGVFFNPUSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50358854   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358854(CHEMBL1923440)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358854(CHEMBL1923440)
Affinity DataIC50:  4nMAssay Description:Inhibition of ATPase activity of recombinant Staphylococcus aureus DNA gyrase B hybrid tetramer enzyme reconstituted from Escherichia coli GyrA by am...More data for this Ligand-Target Pair
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50358854(CHEMBL1923440)
Affinity DataIC50:  160nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed