BDBM50358925 CHEMBL1923682

SMILES COc1ccc2C(N(CCc2c1)S(N)(=O)=O)c1cccc(N)c1

InChI Key InChIKey=OCNXPXPYVLZTMV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50358925   

TargetCarbonic anhydrase 14(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50358925(CHEMBL1923682)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human recombinant full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50358925(CHEMBL1923682)
Affinity DataKi:  18nMAssay Description:Inhibition of human CA9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50358925(CHEMBL1923682)
Affinity DataKi:  99.7nMAssay Description:Inhibition of human recombinant full length CA2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50358925(CHEMBL1923682)
Affinity DataKi:  4.82E+3nMAssay Description:Inhibition of human recombinant full length CA1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed