BDBM503590 US11034670, Ex. 30

SMILES C[C@H]1CN(CCN1C(=O)CCc1nc2cccc(F)c2c(=O)[nH]1)c1ccc(cn1)C#N

InChI Key InChIKey=DUFXFZVTFQWSQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503590   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503590(US11034670, Ex. 30)
Affinity DataIC50: 12nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Mitobridge

US Patent
LigandPNGBDBM503590(US11034670, Ex. 30)
Affinity DataIC50: 624nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent