BDBM50359076 CHEMBL1922656
SMILES CCOc1nc(cs1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c3cc(OCc4ccc(C)cn4)ccc23)cc1
InChI Key InChIKey=JFNPTHBQIWJQNK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50359076
Affinity DataIC50: 419nMAssay Description:Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair