BDBM50359128 CHEMBL1922788::US8921559, 49a::US8921559, 49b

SMILES COC(=O)C(NC1CCC(c2c[nH]c3ccccc23)CC1)C1CCN(C(=O)/C=C/c2cc(F)c(F)c(F)c2)CC1

InChI Key InChIKey=KCFHUAKSGKPHFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359128   

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50359128BDBM50359128(US8921559, 49a | US8921559, 49b | CHEMBL1922788)
Affinity DataIC50: 410nMT: 2°CAssay Description:MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50359128BDBM50359128(US8921559, 49a | US8921559, 49b | CHEMBL1922788)
Affinity DataIC50: 750nMT: 2°CAssay Description:MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50359128BDBM50359128(US8921559, 49a | US8921559, 49b | CHEMBL1922788)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed