BDBM50359252 CHEMBL1923642

SMILES C[C@H]1N(C)C(=O)[C@@H](NCCOc2cc(F)ccc2CCCNC(=O)[C@@H](Cc2ccc(F)cc2)NC1=O)C1CC1

InChI Key InChIKey=XBPLNMSLGBYKCW-UFKXBGGNSA-N

Data  1 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50359252   

TargetAppetite-regulating hormone(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAppetite-regulating hormone(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human GRLN receptor expressed in HEK293 cells assessed as calcium binding by Ca2+ bioluminescence aequorin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359252(CHEMBL1923642)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed