BDBM50359369 CHEMBL1929390

SMILES Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(=O)n2[nH]1

InChI Key InChIKey=KTOQVDYNVULFMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359369   

TargetDipeptidyl peptidase 4(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50359369(CHEMBL1929390)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant DPP-4 using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50359369(CHEMBL1929390)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant DPP-9 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50359369(CHEMBL1929390)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed