BDBM50359522 CHEMBL1927160

SMILES O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCOC3

InChI Key InChIKey=FQIOOGDMVOLMFS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359522   

TargetNADPH oxidase 4(Human)
Genkyotex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359522BDBM50359522(CHEMBL1927160)
Affinity DataKi:  156nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetNADPH oxidase 1(Human)
Genkyotex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359522BDBM50359522(CHEMBL1927160)
Affinity DataKi:  173nMAssay Description:Antagonist activity at human NOX1 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome b-245 heavy chain(Human)
Genkyotex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359522BDBM50359522(CHEMBL1927160)
Affinity DataKi:  433nMAssay Description:Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetNADPH oxidase 5(Human)
Genkyotex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359522BDBM50359522(CHEMBL1927160)
Affinity DataKi:  490nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed