BDBM50360304 CHEMBL516093::US9149492, Beauveriolide I

SMILES CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H](CC(C)C)C(=O)O1

InChI Key InChIKey=ZKSLFHXTWGEITF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50360304   

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 600nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 600nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 780nMAssay Description:Inhibition of ACAT1- mediated cholesteryl ester synthesis in macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 2.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent