BDBM50360574 CHEMBL1933168
SMILES Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O
InChI Key InChIKey=GONILSJCINFJBM-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50360574
Affinity DataEC50: 1.60nMAssay Description:Inhibition of MK2 using Fluo-betaA-11A NeoMPS as substrate pre-incubated for 30 mins before substrate addition measured after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in LPS-stimulated human THP1 cells pre-incubated for 60 mins prior to LPS-induction measured after 6...More data for this Ligand-Target Pair