BDBM50360629 CHEMBL1933725

SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O

InChI Key InChIKey=PBPWYKTUFBNANN-BWVNKGDMSA-N

Data  8 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50360629   

TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human EP4 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP2 subtype(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human EP2 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50360629(CHEMBL1933725)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed