BDBM50361166 CHEMBL4171791

SMILES Clc1ccc(cc1)C(=O)N1CCN2C(C1)C(=O)N(OC(=O)N1CCOc3ccccc13)C2=O

InChI Key InChIKey=JXGBBECNJOFZQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361166   

TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361166(CHEMBL4171791)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NOTUM in human SW620 cells conditioned medium assessed as preservation of Wnt3A activity pretreated for 1 hr followed by Wnt3A producin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50361166(CHEMBL4171791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rhodamine-tagged FP probe binding to NOTUM in human SW620 cells conditioned media pretreated for 30 mins followed by rhodamine-tagged F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed