BDBM503612 2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-3-oxopropyl)quinazolin-4 (3H)-one::US11034670, Ex. 52

SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)CCc1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=CPGPHRFTIHQLET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503612   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503612(2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-3-oxopropy...)
Affinity DataIC50: 68nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Mitobridge

US Patent
LigandPNGBDBM503612(2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-3-oxopropy...)
Affinity DataIC50: 999nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent