BDBM503613 2-(3-(4-(4-fluorophenyl)-3,6-dihydropyridin-1 (2H)-yl)-3-oxopropyl)-7-methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one::US11034670, Ex. 53

SMILES Cn1ccc2c1nc(CCC(=O)N1CCC(=CC1)c1ccc(F)cc1)[nH]c2=O

InChI Key InChIKey=IVINCWLIJUIQAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503613   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM503613(2-(3-(4-(4-fluorophenyl)-3,6-dihydropyridin-1 (2H)...)
Affinity DataIC50: 189nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent