BDBM50362218 CHEMBL1938979

SMILES CN1C[C@@H]2CN(C(=N)c3nc4ccccc4[nH]3)C[C@@H]2C1

InChI Key InChIKey=GVIWSGSJHUJNTC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362218   

TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362218BDBM50362218(CHEMBL1938979)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cells coexpressing Ga15 by radioligand filtration binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362218BDBM50362218(CHEMBL1938979)
Affinity DataKi:  12.4nMAssay Description:Antagonist activity at human histamine H4 receptor expressed in HEK293 cells assessed as rev inhibition of forskolin-stimulated cAMP accumulation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362218BDBM50362218(CHEMBL1938979)
Affinity DataKi:  3.81E+3nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed