BDBM50363270 CHEMBL1944884

SMILES Cc1ccccc1CN(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cnccn1

InChI Key InChIKey=VTEVEQHENPPCQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363270   

TargetNitric oxide synthase, endothelial(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363270(CHEMBL1944884)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363270(CHEMBL1944884)
Affinity DataIC50:  10nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363270(CHEMBL1944884)
Affinity DataIC50:  46nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed