BDBM50363271 CHEMBL1944885

SMILES Fc1ccc2c(CN(Cc3ccccn3)c3cnccn3)cc(=O)[nH]c2c1F

InChI Key InChIKey=IFSBGHCNMNCHCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363271   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363271(CHEMBL1944885)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363271(CHEMBL1944885)
Affinity DataIC50:  78nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363271(CHEMBL1944885)
Affinity DataIC50:  440nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed